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Moreno Lab

Dr. Adrian A. Moreno
adrian.moreno[AT]unab.cl

Dr. Adrian A. Moreno is an Assistant Professor at UNAB (Chile). He is a graduate of the Biochemist from the Faculty of Biological Sciences of the Andres Bello University (UNAB). In 2015 he obtained the degree of Doctor in Biotechnology from the Faculty of Biological Sciences at the Andres Bello University (UNAB). In the period 2015-2016, he developed as a Post-Doctoral Fellow in the Center for Genome Regulation, Chile (CRG-FONDAP). He is academic secretary of Biotechnology Engineer undergrad program from the Faculty of Life Sciences and head of laboratory at the UNAB Center for Plant Biotechnology (CBV).

VRID-UNAB: https://researchers.unab.cl/es/persons/adrian-andres-moreno-vilches
Twitter @Moreno_AA
orcid.org/0000-0001-5125-2927

Molecular basis of the endoplasmic reticulum to the nucleus signaling on plant cells: using the plant response to abiotic and biotic stress as model of study.

Our laboratory is studying the signaling mechanisms associated to the communication between the endoplasmic reticulum and the nucleus of plant cells. Overall, we want to understand how one of the organelles that contribute the most to the proteins and lipids synthesis, is capable to communicate its state of function to the cell nucleus, and how this information is integrated into the cell life and death decisions. An integral part of this communication are the survillance processes such as the endoplasmic reticulum quality control mechanism (ERQC), the endoplasmic reticulum associated degradation of proteins (ERAD) and the unfolded protein response mechanism (UPR). It has been reported that plants with mutations on genes that encode for proteins that participate into these processes,  exhibit a different response than wild type plants to several stresses such as pathogens (bacteria, fungi, virus) or abiotic stresses like heat, salt or drought. The knowledge generated by our investigation is expected to be applied to improve the resistance of plants to these stresses with focus on products of local interest like grapes, berries and cherries.